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Lentz SR, Erger RA, Dayal S, Maeda N, Malinow MR, Heistad DD, and Faraci FM (2000)

For myocardial hypertrophy, potential decisions include who needs closer follow-up, who is likely to progress to HFpEF, who may regress after pressure unloading, who has metabolically reversible remodeling, who should receive a metabolic intervention, and who is at risk of treatment toxicity

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However, the potential immunosuppressive effects of JAK inhibitors also pose challenges, particularly in immunocompromised individuals or those with concurrent infections